Extracellular matrix heterogeneity regulates three-dimensional morphologies of breast adenocarcinoma cell invasion.
نویسندگان
چکیده
Plasticity and reciprocity of breast cancer cells to various extracellular matrice (ECMs) are three-dimensionally analyzed in quantitative way in a novel and powerful microfluidic in vitro platform. This successfully demonstrates the metastatic potential of cancer cells and their effective strategies of ECM proteolytic remodeling and morphological change, while interacting with other cells and invading into heterogeneous ECMs.
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ورودعنوان ژورنال:
- Advanced healthcare materials
دوره 2 6 شماره
صفحات -
تاریخ انتشار 2013